Signs & Symptoms

Signs & Symptoms
Early stages (within 2 years):
– Primary: Painless chancre (genital region), local lymphadenopathy
– Secondary: Maculopapular non-pruritic rash (palms/soles), oral lesions, generalised lymphadenopathy, condyloma lata
– Early latent: Asymptomatic with confirmed infection

Late stages (>2 years):
– Late latent: Asymptomatic with confirmed infection – Tertiary complications:
Neurosyphilis: Meningitis, nerve defects, hearing/vision impairment, generalised paresis
Cardiovascular: Heart failure, aortic aneurysm/regurgitation
Gummatous: Necrotic lesions affecting skin/bones
Pregnancy: Hydrops, preterm labour, low birth weight, congenital syndrome