Referral Criteria & Prognosis

Referral criteria:
– Treatment failure in primary care
– Severe acute reactions
– Food/latex allergies
– Vasculitic urticaria
– Non-blanching purplish/bluish rash
– Painful petechiae with associated symptoms

Pregnancy/breastfeeding considerations:
– Loratadine preferred
– Cetirizine contraindicated with Egfr <15 – Chlorphenamine: Sedating effects
Contraindications (for chlorphenamine):
– Avoid those with hepatic impairment
– Avoid if taking MAOIs (14-day washout)

Prognosis
– Acute cases are typically self-limiting
– Chronic cases may require long-term management