Treatment Plan

Treatment Plan

Angioedema:

• Rapidly progressing: IV chlorphenamine + hydrocortisone, arrange admission
• Stable: Non-sedating oral antihistamines (fexofenadine, loratadine, cetirizine)
• Pregnancy/breastfeeding: Loratadine preferred
• Severe symptoms: short-course oral corticosteroids
• Duration: 6 weeks initially, review
• If persistent: Continue 3-6 months
• If severe urticaria: Continue 6-12 months
• Short-lived symptoms: PRN

Anaphylaxis:

• Call 999
• IM adrenaline (1:1000) outer lateral thigh:

< 6 months: 100-150mcg (0.1-0.15ml)

6m-6y: 150mcg (0.15ml)

6-12y: 300mcg (0.3ml)

> 12y/adults: 500mcg (0.5ml)

Repeat every 5 minutes until improved  – IV chlorphenamine dosing:

< 6m: 250mcg

6m-6y: 2.5mg

6-12 y: 5mg

> 12 y/adults: 10mg

• IV hydrocortisone dosing:

< 6m: 25mg

6m-6y: 50mg

6-12 y: 100mg

> 12 y/adults: 200mg

• Salbutamol nebuliser:

< 6y: 2.5mg

> 6y: 5mg