Alpha Blockers (e.g., Doxazosin, Tamsulosin)
Absolute Contraindications
- History of postural hypotension
- Severe hepatic impairment (for some alpha blockers)
Main Side Effects
- Postural hypotension (especially with the first dose)
- Dizziness, headache
- Fatigue
Main Interactions
- Antihypertensives – additive hypotensive effects
- PDE5 inhibitors (e.g., sildenafil) – risk of severe hypotension
Main Monitoring Requirements
- Blood pressure (especially after the first dose)
Pregnancy & Breastfeeding
- •Limited data, generally avoided unless essential