Hormone Replacement Therapy (HRT)
Oestrogen-only HRT
Absolute Contraindications
- Hormone-sensitive cancer (e.g., breast cancer)
- Active or recent thromboembolic disorders Main Side Effects
- Nausea
- Breast tenderness
Main Interactions
- Enzyme-inducing drugs (e.g., rifampicin, carbamazepine)
Main Monitoring Requirements
- Breast and pelvic examination
- Endometrial thickness in high-risk patients Pregnancy & Breastfeeding
- Not applicable
Combined HRT
Absolute Contraindications
- Hormone-sensitive cancer
- Active or recent thromboembolic disorders Main Side Effects
- Nausea
- Breakthrough bleeding
Main Interactions
- Enzyme-inducing drugs (e.g., rifampicin, carbamazepine)
Main Monitoring Requirements
- Blood pressure
- Breast and pelvic examination Pregnancy & Breastfeeding
- Not applicable
Sequential Combined HRT Absolute Contraindications
- Hormone-sensitive cancer
- Active or recent thromboembolic disorders
Main Side Effects
- Irregular bleeding
- Breast tenderness Main Interactions
- Enzyme-inducing drugs (e.g., rifampicin, carbamazepine) Main Monitoring Requirements
- Regular cycles to ensure compliance
- Breast and pelvic examination
Pregnancy & Breastfeeding
- Not applicable