Treatment & Complications

Treatment

• Bisphosphonates: disease reduction, bone pain
• Anaemia management: EPO, transfusions
• Chemotherapy
• Corticosteroids
• Immunomodulatory drugs
• DVT prophylaxis: aspirin/LMWH
• Stem cell transplantation

Complications

• Pathological fractures
• Spinal cord compression
• Renal damage
• Hypercalcaemia
• Blood hyperviscosity
• Thrombosis
• Bleeding
• Anaemia
• Recurrent infections

CRAB criteria:

C – hypercalcaemia
R – renal impairment
A- anaemia
B – bone pain