Treatment Plan
Treatment Plan
Acute Management:
- Hospital admission if: severe pain unresponsive to analgesia, sepsis, ACS, marked jaundice, neurological/visual changes, acute splenomegaly, priapism
- Low threshold for antibiotics
- Pain relief: paracetamol <13yrs, codeine >13yrs
Prevention:
- Hydroxycarbamide
- Annual influenza vaccination
- Prophylactic antibiotics: Penicillin V (3m-5y), alternative: erythromycin if allergic – Regular blood tests
- Annual transcranial Doppler from age 2
- Eye checks every 2-3y (annual if abnormal)
- Annual growth monitoring
- BP targets: <130/80 if ACR >3.5, <140/90 if normal ACR
- Antihypertensives: ACEi/ARBs if increased ACR, calcium channel blockers if normal ACR
Prognosis
A life-threatening condition requiring ongoing monitoring
Risk of acute complications and chronic organ damage