SIGNS & SYMPTOMS, TREATMENT PLAN

SIGNS & SYMPTOMS 

TREATMENT PLAN 

Types:

• Aspirin
• Clopidogrel, Prasugrel, Ticagrelor (CPT)
• Dipyridamole
• GLP2b/3a inhibitors (abciximab)

Indications:

• Secondary prevention in ACS/angina/PAD/AF (although DOACs are usually prescribed for AF)
• CAD – Aspirin LT
• Cerebrovascular – Clopidogrel LT
• PAD – Clopidogrel LT Specific regimens:
• Post-ACS: Aspirin (lifelong) + second antiplatelet (12 months)
• Post-PCI elective: Aspirin + second antiplatelet (6 months)
• Post-TIA/stroke: Aspirin + clopidogrel (3-4 weeks), then long-term clopidogrel

– If aspirin/clopidogrel contraindicated: Higher dose clopidogrel monotherapy

Medication considerations:

• Avoid omeprazole/esomeprazole with clopidogrel
• Use lansoprazole/pantoprazole if PPI needed

Pre-procedure management (don’t need to stop for dental procedures):

• Clopidogrel: Stop 5-7 days before
• Prasugrel: Stop 7 days before
• Ticagrelor: Stop 3-7 days before