Treatment Plan
Conservative:
• Increased fluid intake
• Increased fibre intake
• Exercise
• Weight loss
• Healthy eating
Medications (escalating approach):
• Bulking Agents (I.Husk/fybogel – important to drink fluids alongside). If not
effective, then add or switch to Osmotic Laxatives (Lactulose, Macrogol, Phosphate,
& Sodium Citrate Enemas)
• If stool is soft or opioid-induced: Stimulant Laxatives (Senna, Bisacodyl) (if soft stool
with difficulty passing)
• For Faucal Loading:
- 1st try Oral methods:
- Hard stool (oral macrogols)
- If still having issues with hard stool/patient has soft stool, try an Oral
stimulant laxative.
- 2nd try rectal methods:
- Soft stool (Bisacodyl)
- Hard stool (Glycerol +/- Bisacodyl)
- If no response, then consider Docusate/sodium Citrate
- If the above fails, you can try Arachis Oil
• For Pregnancy & Breastfeeding:
-
- Bulking agents are 1st line
- Osmotic Laxatives are 2nd line
- If no response, we can consider Glycerol Suppositories
- If the stool is soft/incomplete, the sensation of emptying: Stimulant Laxatives
For chronic cases:
• A 4-week trial of prucalopride (Prokinetic) if the above unsuccessful
• Manual evacuation (for faecal loading)
Contraindications:
• All laxatives are contraindicated in ileus/intestinal obstruction.
• Avoid bulk-forming laxatives in faecal impaction
• Avoid lactulose in galactosemia/IBD
• Avoid arachis oil in peanut allergy