DIFFERENTIALS

DIFFERENTIALS

PCOS triad:

• Ovulatory issues
• Increased hairiness
• Acne with hyperandrogenic activity
• Female androgenic hair loss Androgen-secreting tumours:
• Pelvic/abdominal mass
• Sudden/rapid hair growth despite treatment
• Virilisation signs
  o  Scalp hair loss
  o  Deeper voice
  o  Increased muscle mass
  o Clitoromegaly Other associated conditions:
• Cushing’s o Moon face o Central obesity
• Stretch marks o Easy bruising

• CAH
  • Family history o Menstrual irregularities
    o  Infertility
• Hyperprolactinemia
  o Galactorrhoea
  • Amenorrhoea
  • Infertility
• Acromegaly
  • Increased size of hands/feet o Mandible size changes
    o Frontal bossing & deeper voice
• Hypertrichosis
  o Excess hair growth in general + non-sexual pattern (not linked to androgen levels)