IMPORTANT ASSOCIATED TYPES, SIGNS & SYMPTOMS, INVESTIGATIONS

IMPORTANT ASSOCIATED TYPES

• Early menopause (40-45 years)
• Premature ovarian insufficiency (<40 years)

SIGNS & SYMPTOMS

• Perimenopausal symptoms:
  • Irregular menstrual cycles
  • Vasomotor symptoms: hot flushes, night sweats o Sleep disturbances o Fatigue o Decreased libido o Genitourinary symptoms o Fibromyalgia
  • Vaginitis (vaginal atrophy)

INVESTIGATIONS

FSH measurements indicated for:

• Age >45 with atypical symptoms
• Age 40-45 with symptoms
• Age <40 with suspected premature ovarian insufficiency
• Age >50 using progesterone-only contraception Diagnostic criteria:
• FSH >30 on 2 occasions, 4-6 weeks apart Additional tests: LH, testosterone, oestrogen, TSH

Always important to check BP & BMI